Dermatosis papulosa nigra (DPN) is a benign cutaneous condition common
among blacks. It is usually characterized by multiple, small, hyperpigmented,
asymptomatic papules on the face of adult blacks. Histologically, DPN
resembles seborrheic keratoses. The condition may be cosmetically undesirable
to some patients.
Pathophysiology
The pathophysiology of DPN is not
known. The occasional positive family history may suggest a genetic propensity.
Frequency
United States
Whereas earlier studies revealed a
10% frequency in adult blacks, more recent data suggest a frequency of
approximately 35% in this population.
International
Data pertaining to the
international frequency of DPN are insufficient.
Mortality/Morbidity
DPN is not associated with any
mortality or morbidity.
Race
DPN affects up to 35% of the
African American population. Blacks with a fair complexion have the lowest
frequency of involvement. DPN also occurs among Asians, although the exact
incidence is unknown.
Sex
Females are affected more
frequently than males.
Age
DPN usually begins in adolescence and is rare under the age of 7 years. The
incidence of DPN, as well as the number and size of individual lesions,
increases with age.